diff --git a/src/tests/end2end/MultisampledRenderingTests.cpp b/src/tests/end2end/MultisampledRenderingTests.cpp
index b291487..5360f72 100644
--- a/src/tests/end2end/MultisampledRenderingTests.cpp
+++ b/src/tests/end2end/MultisampledRenderingTests.cpp
@@ -255,6 +255,10 @@
 
 // Test multisampled rendering with depth test works correctly.
 TEST_P(MultisampledRenderingTest, MultisampledRenderingWithDepthTest) {
+    // Test failing on Vulkan with validation layer enabled
+    // See https://bugs.chromium.org/p/dawn/issues/detail?id=210
+    DAWN_SKIP_TEST_IF(IsVulkan() && IsBackendValidationEnabled());
+
     constexpr bool kTestDepth = true;
     dawn::CommandEncoder commandEncoder = device.CreateCommandEncoder();
     dawn::RenderPipeline pipeline = CreateRenderPipelineWithOneOutputForTest(kTestDepth);
diff --git a/src/tests/end2end/TextureZeroInitTests.cpp b/src/tests/end2end/TextureZeroInitTests.cpp
index ac8a304..2d244f9 100644
--- a/src/tests/end2end/TextureZeroInitTests.cpp
+++ b/src/tests/end2end/TextureZeroInitTests.cpp
@@ -300,6 +300,10 @@
 // This tests the texture with depth attachment and load op load will init depth stencil texture to
 // 0s.
 TEST_P(TextureZeroInitTest, RenderingLoadingDepth) {
+    // Test failing on Vulkan with validation layer enabled
+    // See https://bugs.chromium.org/p/dawn/issues/detail?id=210
+    DAWN_SKIP_TEST_IF(IsVulkan() && IsBackendValidationEnabled());
+
     dawn::TextureDescriptor srcDescriptor =
         CreateTextureDescriptor(1, 1,
                                 dawn::TextureUsage::CopySrc | dawn::TextureUsage::CopyDst |
@@ -335,6 +339,10 @@
 // This tests the texture with stencil attachment and load op load will init depth stencil texture
 // to 0s.
 TEST_P(TextureZeroInitTest, RenderingLoadingStencil) {
+    // Test failing on Vulkan with validation layer enabled
+    // See https://bugs.chromium.org/p/dawn/issues/detail?id=210
+    DAWN_SKIP_TEST_IF(IsVulkan() && IsBackendValidationEnabled());
+
     dawn::TextureDescriptor srcDescriptor =
         CreateTextureDescriptor(1, 1,
                                 dawn::TextureUsage::CopySrc | dawn::TextureUsage::CopyDst |
@@ -370,6 +378,10 @@
 // This tests the texture with depth stencil attachment and load op load will init depth stencil
 // texture to 0s.
 TEST_P(TextureZeroInitTest, RenderingLoadingDepthStencil) {
+    // Test failing on Vulkan with validation layer enabled
+    // See https://bugs.chromium.org/p/dawn/issues/detail?id=210
+    DAWN_SKIP_TEST_IF(IsVulkan() && IsBackendValidationEnabled());
+
     dawn::TextureDescriptor srcDescriptor =
         CreateTextureDescriptor(1, 1,
                                 dawn::TextureUsage::CopySrc | dawn::TextureUsage::CopyDst |
diff --git a/src/tests/end2end/VertexInputTests.cpp b/src/tests/end2end/VertexInputTests.cpp
index ae58fd7..e6b1e4a 100644
--- a/src/tests/end2end/VertexInputTests.cpp
+++ b/src/tests/end2end/VertexInputTests.cpp
@@ -523,6 +523,10 @@
 
 // Test that vertex input is not required in render pipeline descriptor.
 TEST_P(OptionalVertexInputTest, Basic) {
+    // Test failing on Vulkan with validation layer enabled
+    // See https://bugs.chromium.org/p/dawn/issues/detail?id=210
+    DAWN_SKIP_TEST_IF(IsVulkan() && IsBackendValidationEnabled());
+
     utils::BasicRenderPass renderPass = utils::CreateBasicRenderPass(device, 3, 3);
 
     dawn::ShaderModule vsModule =