diff --git a/src/dawn/native/Blob.cpp b/src/dawn/native/Blob.cpp
index cecac30..78b18e7 100644
--- a/src/dawn/native/Blob.cpp
+++ b/src/dawn/native/Blob.cpp
@@ -17,6 +17,7 @@
 #include "dawn/common/Assert.h"
 #include "dawn/common/Math.h"
 #include "dawn/native/Blob.h"
+#include "dawn/native/stream/Stream.h"
 
 namespace dawn::native {
 
@@ -99,4 +100,29 @@
     *this = std::move(blob);
 }
 
+template <>
+void stream::Stream<Blob>::Write(stream::Sink* s, const Blob& b) {
+    size_t size = b.Size();
+    StreamIn(s, size);
+    if (size > 0) {
+        void* ptr = s->GetSpace(size);
+        memcpy(ptr, b.Data(), size);
+    }
+}
+
+template <>
+MaybeError stream::Stream<Blob>::Read(stream::Source* s, Blob* b) {
+    size_t size;
+    DAWN_TRY(StreamOut(s, &size));
+    if (size > 0) {
+        const void* ptr;
+        DAWN_TRY(s->Read(&ptr, size));
+        *b = CreateBlob(size);
+        memcpy(b->Data(), ptr, size);
+    } else {
+        *b = Blob();
+    }
+    return {};
+}
+
 }  // namespace dawn::native
diff --git a/src/dawn/native/StreamImplTint.cpp b/src/dawn/native/StreamImplTint.cpp
index 1c0c04d..13a70ca 100644
--- a/src/dawn/native/StreamImplTint.cpp
+++ b/src/dawn/native/StreamImplTint.cpp
@@ -14,7 +14,8 @@
 
 #include "dawn/native/stream/Stream.h"
 
-#include "tint/tint.h"
+#include "dawn/native/TintUtils.h"
+#include "tint/writer/array_length_from_uniform_options.h"
 
 namespace dawn::native {
 
@@ -96,4 +97,21 @@
     StreamIn(sink, attrib.format, attrib.offset, attrib.shader_location);
 }
 
+// static
+template <>
+void stream::Stream<tint::writer::ArrayLengthFromUniformOptions>::Write(
+    stream::Sink* sink,
+    const tint::writer::ArrayLengthFromUniformOptions& o) {
+    static_assert(offsetof(tint::writer::ArrayLengthFromUniformOptions, ubo_binding) == 0,
+                  "Please update serialization for tint::writer::ArrayLengthFromUniformOptions");
+    static_assert(
+        offsetof(tint::writer::ArrayLengthFromUniformOptions, bindpoint_to_size_index) == 8,
+        "Please update serialization for tint::writer::ArrayLengthFromUniformOptions");
+    static_assert(
+        sizeof(tint::writer::ArrayLengthFromUniformOptions) ==
+            8 + sizeof(tint::writer::ArrayLengthFromUniformOptions::bindpoint_to_size_index),
+        "Please update serialization for tint::writer::ArrayLengthFromUniformOptions");
+    StreamIn(sink, o.ubo_binding, o.bindpoint_to_size_index);
+}
+
 }  // namespace dawn::native
diff --git a/src/dawn/native/TintUtils.cpp b/src/dawn/native/TintUtils.cpp
index c1585a5..f59e6e5 100644
--- a/src/dawn/native/TintUtils.cpp
+++ b/src/dawn/native/TintUtils.cpp
@@ -185,7 +185,10 @@
 
 }  // namespace dawn::native
 
-bool std::less<tint::sem::BindingPoint>::operator()(const tint::sem::BindingPoint& a,
-                                                    const tint::sem::BindingPoint& b) const {
+namespace tint::sem {
+
+bool operator<(const BindingPoint& a, const BindingPoint& b) {
     return std::tie(a.group, a.binding) < std::tie(b.group, b.binding);
 }
+
+}  // namespace tint::sem
diff --git a/src/dawn/native/TintUtils.h b/src/dawn/native/TintUtils.h
index e17fc69..7c03881 100644
--- a/src/dawn/native/TintUtils.h
+++ b/src/dawn/native/TintUtils.h
@@ -49,10 +49,11 @@
 
 }  // namespace dawn::native
 
-// std::less operator for std::map containing BindingPoint
-template <>
-struct std::less<tint::sem::BindingPoint> {
-    bool operator()(const tint::sem::BindingPoint& a, const tint::sem::BindingPoint& b) const;
-};
+namespace tint::sem {
+
+// Defin operator< for std::map containing BindingPoint
+bool operator<(const BindingPoint& a, const BindingPoint& b);
+
+}  // namespace tint::sem
 
 #endif  // SRC_DAWN_NATIVE_TINTUTILS_H_
diff --git a/src/dawn/native/d3d12/BlobD3D12.cpp b/src/dawn/native/d3d12/BlobD3D12.cpp
index ef9bbb9..3b596575 100644
--- a/src/dawn/native/d3d12/BlobD3D12.cpp
+++ b/src/dawn/native/d3d12/BlobD3D12.cpp
@@ -28,4 +28,16 @@
                                          });
 }
 
+Blob CreateBlob(ComPtr<IDxcBlob> blob) {
+    // Detach so the deleter callback can "own" the reference
+    IDxcBlob* ptr = blob.Detach();
+    return Blob::UnsafeCreateWithDeleter(reinterpret_cast<uint8_t*>(ptr->GetBufferPointer()),
+                                         ptr->GetBufferSize(), [=]() {
+                                             // Reattach and drop to delete it.
+                                             ComPtr<IDxcBlob> b;
+                                             b.Attach(ptr);
+                                             b = nullptr;
+                                         });
+}
+
 }  // namespace dawn::native
diff --git a/src/dawn/native/d3d12/BlobD3D12.h b/src/dawn/native/d3d12/BlobD3D12.h
index 563ac73..cc8c99c 100644
--- a/src/dawn/native/d3d12/BlobD3D12.h
+++ b/src/dawn/native/d3d12/BlobD3D12.h
@@ -18,5 +18,6 @@
 namespace dawn::native {
 
 Blob CreateBlob(ComPtr<ID3DBlob> blob);
+Blob CreateBlob(ComPtr<IDxcBlob> blob);
 
 }  // namespace dawn::native
diff --git a/src/dawn/native/d3d12/ShaderModuleD3D12.cpp b/src/dawn/native/d3d12/ShaderModuleD3D12.cpp
index 3e09cc0..2fd04bd 100644
--- a/src/dawn/native/d3d12/ShaderModuleD3D12.cpp
+++ b/src/dawn/native/d3d12/ShaderModuleD3D12.cpp
@@ -29,79 +29,41 @@
 #include "dawn/common/Log.h"
 #include "dawn/common/WindowsUtils.h"
 #include "dawn/native/CacheKey.h"
+#include "dawn/native/CacheRequest.h"
 #include "dawn/native/Pipeline.h"
 #include "dawn/native/TintUtils.h"
 #include "dawn/native/d3d12/AdapterD3D12.h"
 #include "dawn/native/d3d12/BackendD3D12.h"
 #include "dawn/native/d3d12/BindGroupLayoutD3D12.h"
+#include "dawn/native/d3d12/BlobD3D12.h"
 #include "dawn/native/d3d12/D3D12Error.h"
 #include "dawn/native/d3d12/DeviceD3D12.h"
 #include "dawn/native/d3d12/PipelineLayoutD3D12.h"
 #include "dawn/native/d3d12/PlatformFunctions.h"
 #include "dawn/native/d3d12/UtilsD3D12.h"
+#include "dawn/native/stream/BlobSource.h"
+#include "dawn/native/stream/ByteVectorSink.h"
 #include "dawn/platform/DawnPlatform.h"
 #include "dawn/platform/tracing/TraceEvent.h"
 
 #include "tint/tint.h"
 
+namespace dawn::native::stream {
+
+// Define no-op serializations for pD3DCompile, IDxcLibrary, and IDxcCompiler.
+// These are output-only interfaces used to generate bytecode.
+template <>
+void Stream<IDxcLibrary*>::Write(Sink*, IDxcLibrary* const&) {}
+template <>
+void Stream<IDxcCompiler*>::Write(Sink*, IDxcCompiler* const&) {}
+template <>
+void Stream<pD3DCompile>::Write(Sink*, pD3DCompile const&) {}
+
+}  // namespace dawn::native::stream
+
 namespace dawn::native::d3d12 {
 
 namespace {
-uint64_t GetD3DCompilerVersion() {
-    return D3D_COMPILER_VERSION;
-}
-
-struct CompareBindingPoint {
-    constexpr bool operator()(const tint::transform::BindingPoint& lhs,
-                              const tint::transform::BindingPoint& rhs) const {
-        if (lhs.group != rhs.group) {
-            return lhs.group < rhs.group;
-        } else {
-            return lhs.binding < rhs.binding;
-        }
-    }
-};
-
-void StreamIn(std::stringstream& output, const tint::ast::Access& access) {
-    output << access;
-}
-
-void StreamIn(std::stringstream& output, const tint::transform::BindingPoint& binding_point) {
-    output << "(BindingPoint";
-    output << " group=" << binding_point.group;
-    output << " binding=" << binding_point.binding;
-    output << ")";
-}
-
-template <typename T, typename = typename std::enable_if<std::is_fundamental<T>::value>::type>
-void StreamIn(std::stringstream& output, const T& val) {
-    output << val;
-}
-
-template <typename T>
-void StreamIn(std::stringstream& output,
-              const std::unordered_map<tint::transform::BindingPoint, T>& map) {
-    output << "(map";
-
-    std::map<tint::transform::BindingPoint, T, CompareBindingPoint> sorted(map.begin(), map.end());
-    for (auto& [bindingPoint, value] : sorted) {
-        output << " ";
-        StreamIn(output, bindingPoint);
-        output << "=";
-        StreamIn(output, value);
-    }
-    output << ")";
-}
-
-void StreamIn(std::stringstream& output,
-              const tint::writer::ArrayLengthFromUniformOptions& arrayLengthFromUniform) {
-    output << "(ArrayLengthFromUniformOptions";
-    output << " ubo_binding=";
-    StreamIn(output, arrayLengthFromUniform.ubo_binding);
-    output << " bindpoint_to_size_index=";
-    StreamIn(output, arrayLengthFromUniform.bindpoint_to_size_index);
-    output << ")";
-}
 
 // 32 bit float has 7 decimal digits of precision so setting n to 8 should be enough
 std::string FloatToStringWithPrecision(float v, std::streamsize n = 8) {
@@ -130,253 +92,113 @@
 
 constexpr char kSpecConstantPrefix[] = "WGSL_SPEC_CONSTANT_";
 
-void GetOverridableConstantsDefines(
-    std::vector<std::pair<std::string, std::string>>* defineStrings,
-    const PipelineConstantEntries* pipelineConstantEntries,
-    const EntryPointMetadata::OverridesMap* shaderEntryPointConstants) {
+using DefineStrings = std::vector<std::pair<std::string, std::string>>;
+
+DefineStrings GetOverridableConstantsDefines(
+    const PipelineConstantEntries& pipelineConstantEntries,
+    const EntryPointMetadata::OverridesMap& shaderEntryPointConstants) {
+    DefineStrings defineStrings;
     std::unordered_set<std::string> overriddenConstants;
 
     // Set pipeline overridden values
-    for (const auto& [name, value] : *pipelineConstantEntries) {
+    for (const auto& [name, value] : pipelineConstantEntries) {
         overriddenConstants.insert(name);
 
         // This is already validated so `name` must exist
-        const auto& moduleConstant = shaderEntryPointConstants->at(name);
+        const auto& moduleConstant = shaderEntryPointConstants.at(name);
 
-        defineStrings->emplace_back(
+        defineStrings.emplace_back(
             kSpecConstantPrefix + std::to_string(static_cast<int32_t>(moduleConstant.id)),
             GetHLSLValueString(moduleConstant.type, nullptr, value));
     }
 
     // Set shader initialized default values
-    for (const auto& iter : *shaderEntryPointConstants) {
+    for (const auto& iter : shaderEntryPointConstants) {
         const std::string& name = iter.first;
         if (overriddenConstants.count(name) != 0) {
             // This constant already has overridden value
             continue;
         }
 
-        const auto& moduleConstant = shaderEntryPointConstants->at(name);
+        const auto& moduleConstant = shaderEntryPointConstants.at(name);
 
         // Uninitialized default values are okay since they ar only defined to pass
         // compilation but not used
-        defineStrings->emplace_back(
+        defineStrings.emplace_back(
             kSpecConstantPrefix + std::to_string(static_cast<int32_t>(moduleConstant.id)),
             GetHLSLValueString(moduleConstant.type, &moduleConstant.defaultValue));
     }
+    return defineStrings;
 }
 
-// The inputs to a shader compilation. These have been intentionally isolated from the
-// device to help ensure that the pipeline cache key contains all inputs for compilation.
-struct ShaderCompilationRequest {
-    enum Compiler { FXC, DXC };
+enum class Compiler { FXC, DXC };
 
-    // Common inputs
-    Compiler compiler;
-    const tint::Program* program;
-    const char* entryPointName;
-    SingleShaderStage stage;
-    uint32_t compileFlags;
-    bool disableSymbolRenaming;
-    tint::transform::BindingRemapper::BindingPoints remappedBindingPoints;
-    tint::transform::BindingRemapper::AccessControls remappedAccessControls;
-    bool isRobustnessEnabled;
-    bool usesNumWorkgroups;
-    uint32_t numWorkgroupsRegisterSpace;
-    uint32_t numWorkgroupsShaderRegister;
-    tint::writer::ArrayLengthFromUniformOptions arrayLengthFromUniform;
-    std::vector<std::pair<std::string, std::string>> defineStrings;
+#define HLSL_COMPILATION_REQUEST_MEMBERS(X)                                     \
+    X(const tint::Program*, inputProgram)                                       \
+    X(std::string_view, entryPointName)                                         \
+    X(SingleShaderStage, stage)                                                 \
+    X(uint32_t, shaderModel)                                                    \
+    X(uint32_t, compileFlags)                                                   \
+    X(Compiler, compiler)                                                       \
+    X(uint64_t, compilerVersion)                                                \
+    X(std::wstring_view, dxcShaderProfile)                                      \
+    X(std::string_view, fxcShaderProfile)                                       \
+    X(pD3DCompile, d3dCompile)                                                  \
+    X(IDxcLibrary*, dxcLibrary)                                                 \
+    X(IDxcCompiler*, dxcCompiler)                                               \
+    X(uint32_t, firstIndexOffsetShaderRegister)                                 \
+    X(uint32_t, firstIndexOffsetRegisterSpace)                                  \
+    X(bool, usesNumWorkgroups)                                                  \
+    X(uint32_t, numWorkgroupsShaderRegister)                                    \
+    X(uint32_t, numWorkgroupsRegisterSpace)                                     \
+    X(DefineStrings, defineStrings)                                             \
+    X(tint::transform::MultiplanarExternalTexture::BindingsMap, newBindingsMap) \
+    X(tint::writer::ArrayLengthFromUniformOptions, arrayLengthFromUniform)      \
+    X(tint::transform::BindingRemapper::BindingPoints, remappedBindingPoints)   \
+    X(tint::transform::BindingRemapper::AccessControls, remappedAccessControls) \
+    X(bool, disableSymbolRenaming)                                              \
+    X(bool, isRobustnessEnabled)                                                \
+    X(bool, disableWorkgroupInit)                                               \
+    X(bool, dumpShaders)
 
-    // FXC/DXC common inputs
-    bool disableWorkgroupInit;
+#define D3D_BYTECODE_COMPILATION_REQUEST_MEMBERS(X) \
+    X(bool, hasShaderFloat16Feature)                \
+    X(uint32_t, compileFlags)                       \
+    X(Compiler, compiler)                           \
+    X(uint64_t, compilerVersion)                    \
+    X(std::wstring_view, dxcShaderProfile)          \
+    X(std::string_view, fxcShaderProfile)           \
+    X(pD3DCompile, d3dCompile)                      \
+    X(IDxcLibrary*, dxcLibrary)                     \
+    X(IDxcCompiler*, dxcCompiler)                   \
+    X(DefineStrings, defineStrings)
 
-    // FXC inputs
-    uint64_t fxcVersion;
+struct HlslCompilationRequest {
+    DAWN_VISITABLE_MEMBERS(HLSL_COMPILATION_REQUEST_MEMBERS)
 
-    // DXC inputs
-    uint64_t dxcVersion;
-    const D3D12DeviceInfo* deviceInfo;
-    bool hasShaderFloat16Feature;
-
-    static ResultOrError<ShaderCompilationRequest> Create(
-        const char* entryPointName,
-        SingleShaderStage stage,
-        const PipelineLayout* layout,
-        uint32_t compileFlags,
-        const Device* device,
-        const tint::Program* program,
-        const EntryPointMetadata& entryPoint,
-        const ProgrammableStage& programmableStage) {
-        Compiler compiler;
-        uint64_t dxcVersion = 0;
-        if (device->IsToggleEnabled(Toggle::UseDXC)) {
-            compiler = Compiler::DXC;
-            DAWN_TRY_ASSIGN(dxcVersion,
-                            ToBackend(device->GetAdapter())->GetBackend()->GetDXCompilerVersion());
-        } else {
-            compiler = Compiler::FXC;
-        }
-
-        using tint::transform::BindingPoint;
-        using tint::transform::BindingRemapper;
-
-        BindingRemapper::BindingPoints remappedBindingPoints;
-        BindingRemapper::AccessControls remappedAccessControls;
-
-        tint::writer::ArrayLengthFromUniformOptions arrayLengthFromUniform;
-        arrayLengthFromUniform.ubo_binding = {
-            layout->GetDynamicStorageBufferLengthsRegisterSpace(),
-            layout->GetDynamicStorageBufferLengthsShaderRegister()};
-
-        const BindingInfoArray& moduleBindingInfo = entryPoint.bindings;
-        for (BindGroupIndex group : IterateBitSet(layout->GetBindGroupLayoutsMask())) {
-            const BindGroupLayout* bgl = ToBackend(layout->GetBindGroupLayout(group));
-            const auto& groupBindingInfo = moduleBindingInfo[group];
-
-            // d3d12::BindGroupLayout packs the bindings per HLSL register-space. We modify
-            // the Tint AST to make the "bindings" decoration match the offset chosen by
-            // d3d12::BindGroupLayout so that Tint produces HLSL with the correct registers
-            // assigned to each interface variable.
-            for (const auto& [binding, bindingInfo] : groupBindingInfo) {
-                BindingIndex bindingIndex = bgl->GetBindingIndex(binding);
-                BindingPoint srcBindingPoint{static_cast<uint32_t>(group),
-                                             static_cast<uint32_t>(binding)};
-                BindingPoint dstBindingPoint{static_cast<uint32_t>(group),
-                                             bgl->GetShaderRegister(bindingIndex)};
-                if (srcBindingPoint != dstBindingPoint) {
-                    remappedBindingPoints.emplace(srcBindingPoint, dstBindingPoint);
-                }
-
-                // Declaring a read-only storage buffer in HLSL but specifying a storage
-                // buffer in the BGL produces the wrong output. Force read-only storage
-                // buffer bindings to be treated as UAV instead of SRV. Internal storage
-                // buffer is a storage buffer used in the internal pipeline.
-                const bool forceStorageBufferAsUAV =
-                    (bindingInfo.buffer.type == wgpu::BufferBindingType::ReadOnlyStorage &&
-                     (bgl->GetBindingInfo(bindingIndex).buffer.type ==
-                          wgpu::BufferBindingType::Storage ||
-                      bgl->GetBindingInfo(bindingIndex).buffer.type ==
-                          kInternalStorageBufferBinding));
-                if (forceStorageBufferAsUAV) {
-                    remappedAccessControls.emplace(srcBindingPoint, tint::ast::Access::kReadWrite);
-                }
-            }
-
-            // Add arrayLengthFromUniform options
-            {
-                for (const auto& bindingAndRegisterOffset :
-                     layout->GetDynamicStorageBufferLengthInfo()[group].bindingAndRegisterOffsets) {
-                    BindingNumber binding = bindingAndRegisterOffset.binding;
-                    uint32_t registerOffset = bindingAndRegisterOffset.registerOffset;
-
-                    BindingPoint bindingPoint{static_cast<uint32_t>(group),
-                                              static_cast<uint32_t>(binding)};
-                    // Get the renamed binding point if it was remapped.
-                    auto it = remappedBindingPoints.find(bindingPoint);
-                    if (it != remappedBindingPoints.end()) {
-                        bindingPoint = it->second;
-                    }
-
-                    arrayLengthFromUniform.bindpoint_to_size_index.emplace(bindingPoint,
-                                                                           registerOffset);
-                }
-            }
-        }
-
-        ShaderCompilationRequest request;
-        request.compiler = compiler;
-        request.program = program;
-        request.entryPointName = entryPointName;
-        request.stage = stage;
-        request.compileFlags = compileFlags;
-        request.disableSymbolRenaming = device->IsToggleEnabled(Toggle::DisableSymbolRenaming);
-        request.remappedBindingPoints = std::move(remappedBindingPoints);
-        request.remappedAccessControls = std::move(remappedAccessControls);
-        request.isRobustnessEnabled = device->IsRobustnessEnabled();
-        request.disableWorkgroupInit = device->IsToggleEnabled(Toggle::DisableWorkgroupInit);
-        request.usesNumWorkgroups = entryPoint.usesNumWorkgroups;
-        request.numWorkgroupsShaderRegister = layout->GetNumWorkgroupsShaderRegister();
-        request.numWorkgroupsRegisterSpace = layout->GetNumWorkgroupsRegisterSpace();
-        request.arrayLengthFromUniform = std::move(arrayLengthFromUniform);
-        request.fxcVersion = compiler == Compiler::FXC ? GetD3DCompilerVersion() : 0;
-        request.dxcVersion = compiler == Compiler::DXC ? dxcVersion : 0;
-        request.deviceInfo = &device->GetDeviceInfo();
-        request.hasShaderFloat16Feature = device->IsFeatureEnabled(Feature::ShaderFloat16);
-
-        GetOverridableConstantsDefines(
-            &request.defineStrings, &programmableStage.constants,
-            &programmableStage.module->GetEntryPoint(programmableStage.entryPoint).overrides);
-
-        return std::move(request);
-    }
-
-    // TODO(dawn:1341): Move to use CacheKey instead of the vector.
-    ResultOrError<std::vector<uint8_t>> CreateCacheKey() const {
-        // Generate the WGSL from the Tint program so it's normalized.
-        // TODO(tint:1180): Consider using a binary serialization of the tint AST for a more
-        // compact representation.
-        auto result = tint::writer::wgsl::Generate(program, tint::writer::wgsl::Options{});
-        if (!result.success) {
-            std::ostringstream errorStream;
-            errorStream << "Tint WGSL failure:" << std::endl;
-            errorStream << "Generator: " << result.error << std::endl;
-            return DAWN_INTERNAL_ERROR(errorStream.str().c_str());
-        }
-
-        std::stringstream stream;
-
-        // Prefix the key with the type to avoid collisions from another type that could
-        // have the same key.
-        stream << static_cast<uint32_t>(CacheKey::Type::Shader);
-        stream << "\n";
-
-        stream << result.wgsl.length();
-        stream << "\n";
-
-        stream << result.wgsl;
-        stream << "\n";
-
-        stream << "(ShaderCompilationRequest";
-        stream << " compiler=" << compiler;
-        stream << " entryPointName=" << entryPointName;
-        stream << " stage=" << uint32_t(stage);
-        stream << " compileFlags=" << compileFlags;
-        stream << " disableSymbolRenaming=" << disableSymbolRenaming;
-
-        stream << " remappedBindingPoints=";
-        StreamIn(stream, remappedBindingPoints);
-
-        stream << " remappedAccessControls=";
-        StreamIn(stream, remappedAccessControls);
-
-        stream << " useNumWorkgroups=" << usesNumWorkgroups;
-        stream << " numWorkgroupsRegisterSpace=" << numWorkgroupsRegisterSpace;
-        stream << " numWorkgroupsShaderRegister=" << numWorkgroupsShaderRegister;
-
-        stream << " arrayLengthFromUniform=";
-        StreamIn(stream, arrayLengthFromUniform);
-
-        stream << " shaderModel=" << deviceInfo->shaderModel;
-        stream << " disableWorkgroupInit=" << disableWorkgroupInit;
-        stream << " isRobustnessEnabled=" << isRobustnessEnabled;
-        stream << " fxcVersion=" << fxcVersion;
-        stream << " dxcVersion=" << dxcVersion;
-        stream << " hasShaderFloat16Feature=" << hasShaderFloat16Feature;
-
-        stream << " defines={";
-        for (const auto& [name, value] : defineStrings) {
-            stream << " <" << name << "," << value << ">";
-        }
-        stream << " }";
-
-        stream << ")";
-        stream << "\n";
-
-        return std::vector<uint8_t>(std::istreambuf_iterator<char>{stream},
-                                    std::istreambuf_iterator<char>{});
+    friend void StreamIn(stream::Sink* sink, const HlslCompilationRequest& r) {
+        r.VisitAll([&](const auto&... members) { StreamIn(sink, members...); });
     }
 };
 
+struct D3DBytecodeCompilationRequest {
+    DAWN_VISITABLE_MEMBERS(D3D_BYTECODE_COMPILATION_REQUEST_MEMBERS)
+
+    friend void StreamIn(stream::Sink* sink, const D3DBytecodeCompilationRequest& r) {
+        r.VisitAll([&](const auto&... members) { StreamIn(sink, members...); });
+    }
+};
+
+#define D3D_COMPILATION_REQUEST_MEMBERS(X)     \
+    X(HlslCompilationRequest, hlsl)            \
+    X(D3DBytecodeCompilationRequest, bytecode) \
+    X(CacheKey::UnsafeUnkeyedValue<dawn::platform::Platform*>, tracePlatform)
+
+DAWN_MAKE_CACHE_REQUEST(D3DCompilationRequest, D3D_COMPILATION_REQUEST_MEMBERS);
+#undef HLSL_COMPILATION_REQUEST_MEMBERS
+#undef D3D_BYTECODE_COMPILATION_REQUEST_MEMBERS
+#undef D3D_COMPILATION_REQUEST_MEMBERS
+
 std::vector<const wchar_t*> GetDXCArguments(uint32_t compileFlags, bool enable16BitTypes) {
     std::vector<const wchar_t*> arguments;
     if (compileFlags & D3DCOMPILE_ENABLE_BACKWARDS_COMPATIBILITY) {
@@ -429,25 +251,24 @@
     return arguments;
 }
 
-ResultOrError<ComPtr<IDxcBlob>> CompileShaderDXC(IDxcLibrary* dxcLibrary,
-                                                 IDxcCompiler* dxcCompiler,
-                                                 const ShaderCompilationRequest& request,
+ResultOrError<ComPtr<IDxcBlob>> CompileShaderDXC(const D3DBytecodeCompilationRequest& r,
+                                                 const std::string& entryPointName,
                                                  const std::string& hlslSource) {
     ComPtr<IDxcBlobEncoding> sourceBlob;
-    DAWN_TRY(CheckHRESULT(dxcLibrary->CreateBlobWithEncodingOnHeapCopy(
+    DAWN_TRY(CheckHRESULT(r.dxcLibrary->CreateBlobWithEncodingFromPinned(
                               hlslSource.c_str(), hlslSource.length(), CP_UTF8, &sourceBlob),
                           "DXC create blob"));
 
     std::wstring entryPointW;
-    DAWN_TRY_ASSIGN(entryPointW, ConvertStringToWstring(request.entryPointName));
+    DAWN_TRY_ASSIGN(entryPointW, ConvertStringToWstring(entryPointName));
 
     std::vector<const wchar_t*> arguments =
-        GetDXCArguments(request.compileFlags, request.hasShaderFloat16Feature);
+        GetDXCArguments(r.compileFlags, r.hasShaderFloat16Feature);
 
     // Build defines for overridable constants
     std::vector<std::pair<std::wstring, std::wstring>> defineStrings;
-    defineStrings.reserve(request.defineStrings.size());
-    for (const auto& [name, value] : request.defineStrings) {
+    defineStrings.reserve(r.defineStrings.size());
+    for (const auto& [name, value] : r.defineStrings) {
         defineStrings.emplace_back(UTF8ToWStr(name.c_str()), UTF8ToWStr(value.c_str()));
     }
 
@@ -458,12 +279,11 @@
     }
 
     ComPtr<IDxcOperationResult> result;
-    DAWN_TRY(
-        CheckHRESULT(dxcCompiler->Compile(sourceBlob.Get(), nullptr, entryPointW.c_str(),
-                                          request.deviceInfo->shaderProfiles[request.stage].c_str(),
-                                          arguments.data(), arguments.size(), dxcDefines.data(),
-                                          dxcDefines.size(), nullptr, &result),
-                     "DXC compile"));
+    DAWN_TRY(CheckHRESULT(
+        r.dxcCompiler->Compile(sourceBlob.Get(), nullptr, entryPointW.c_str(),
+                               r.dxcShaderProfile.data(), arguments.data(), arguments.size(),
+                               dxcDefines.data(), dxcDefines.size(), nullptr, &result),
+        "DXC compile"));
 
     HRESULT hr;
     DAWN_TRY(CheckHRESULT(result->GetStatus(&hr), "DXC get status"));
@@ -543,31 +363,18 @@
     return result;
 }
 
-ResultOrError<ComPtr<ID3DBlob>> CompileShaderFXC(const PlatformFunctions* functions,
-                                                 const ShaderCompilationRequest& request,
+ResultOrError<ComPtr<ID3DBlob>> CompileShaderFXC(const D3DBytecodeCompilationRequest& r,
+                                                 const std::string& entryPointName,
                                                  const std::string& hlslSource) {
-    const char* targetProfile = nullptr;
-    switch (request.stage) {
-        case SingleShaderStage::Vertex:
-            targetProfile = "vs_5_1";
-            break;
-        case SingleShaderStage::Fragment:
-            targetProfile = "ps_5_1";
-            break;
-        case SingleShaderStage::Compute:
-            targetProfile = "cs_5_1";
-            break;
-    }
-
     ComPtr<ID3DBlob> compiledShader;
     ComPtr<ID3DBlob> errors;
 
     // Build defines for overridable constants
     const D3D_SHADER_MACRO* pDefines = nullptr;
     std::vector<D3D_SHADER_MACRO> fxcDefines;
-    if (request.defineStrings.size() > 0) {
-        fxcDefines.reserve(request.defineStrings.size() + 1);
-        for (const auto& [name, value] : request.defineStrings) {
+    if (r.defineStrings.size() > 0) {
+        fxcDefines.reserve(r.defineStrings.size() + 1);
+        for (const auto& [name, value] : r.defineStrings) {
             fxcDefines.push_back({name.c_str(), value.c_str()});
         }
         // d3dCompile D3D_SHADER_MACRO* pDefines is a nullptr terminated array
@@ -575,36 +382,49 @@
         pDefines = fxcDefines.data();
     }
 
-    DAWN_INVALID_IF(
-        FAILED(functions->d3dCompile(hlslSource.c_str(), hlslSource.length(), nullptr, pDefines,
-                                     nullptr, request.entryPointName, targetProfile,
-                                     request.compileFlags, 0, &compiledShader, &errors)),
-        "D3D compile failed with: %s", static_cast<char*>(errors->GetBufferPointer()));
+    DAWN_INVALID_IF(FAILED(r.d3dCompile(hlslSource.c_str(), hlslSource.length(), nullptr, pDefines,
+                                        nullptr, entryPointName.c_str(), r.fxcShaderProfile.data(),
+                                        r.compileFlags, 0, &compiledShader, &errors)),
+                    "D3D compile failed with: %s", static_cast<char*>(errors->GetBufferPointer()));
 
     return std::move(compiledShader);
 }
 
-ResultOrError<std::string> TranslateToHLSL(dawn::platform::Platform* platform,
-                                           const ShaderCompilationRequest& request,
-                                           std::string* remappedEntryPointName) {
+ResultOrError<std::string> TranslateToHLSL(
+    HlslCompilationRequest r,
+    CacheKey::UnsafeUnkeyedValue<dawn::platform::Platform*> tracePlatform,
+    std::string* remappedEntryPointName,
+    bool* usesVertexOrInstanceIndex) {
     std::ostringstream errorStream;
     errorStream << "Tint HLSL failure:" << std::endl;
 
     tint::transform::Manager transformManager;
     tint::transform::DataMap transformInputs;
 
-    if (request.isRobustnessEnabled) {
+    if (!r.newBindingsMap.empty()) {
+        transformManager.Add<tint::transform::MultiplanarExternalTexture>();
+        transformInputs.Add<tint::transform::MultiplanarExternalTexture::NewBindingPoints>(
+            std::move(r.newBindingsMap));
+    }
+
+    if (r.stage == SingleShaderStage::Vertex) {
+        transformManager.Add<tint::transform::FirstIndexOffset>();
+        transformInputs.Add<tint::transform::FirstIndexOffset::BindingPoint>(
+            r.firstIndexOffsetShaderRegister, r.firstIndexOffsetRegisterSpace);
+    }
+
+    if (r.isRobustnessEnabled) {
         transformManager.Add<tint::transform::Robustness>();
     }
 
     transformManager.Add<tint::transform::BindingRemapper>();
 
     transformManager.Add<tint::transform::SingleEntryPoint>();
-    transformInputs.Add<tint::transform::SingleEntryPoint::Config>(request.entryPointName);
+    transformInputs.Add<tint::transform::SingleEntryPoint::Config>(r.entryPointName.data());
 
     transformManager.Add<tint::transform::Renamer>();
 
-    if (request.disableSymbolRenaming) {
+    if (r.disableSymbolRenaming) {
         // We still need to rename HLSL reserved keywords
         transformInputs.Add<tint::transform::Renamer::Config>(
             tint::transform::Renamer::Target::kHlslKeywords);
@@ -615,104 +435,92 @@
     // different types.
     const bool mayCollide = true;
     transformInputs.Add<tint::transform::BindingRemapper::Remappings>(
-        std::move(request.remappedBindingPoints), std::move(request.remappedAccessControls),
-        mayCollide);
+        std::move(r.remappedBindingPoints), std::move(r.remappedAccessControls), mayCollide);
 
     tint::Program transformedProgram;
     tint::transform::DataMap transformOutputs;
     {
-        TRACE_EVENT0(platform, General, "RunTransforms");
+        TRACE_EVENT0(tracePlatform.UnsafeGetValue(), General, "RunTransforms");
         DAWN_TRY_ASSIGN(transformedProgram,
-                        RunTransforms(&transformManager, request.program, transformInputs,
+                        RunTransforms(&transformManager, r.inputProgram, transformInputs,
                                       &transformOutputs, nullptr));
     }
 
     if (auto* data = transformOutputs.Get<tint::transform::Renamer::Data>()) {
-        auto it = data->remappings.find(request.entryPointName);
+        auto it = data->remappings.find(r.entryPointName.data());
         if (it != data->remappings.end()) {
             *remappedEntryPointName = it->second;
         } else {
-            DAWN_INVALID_IF(!request.disableSymbolRenaming,
+            DAWN_INVALID_IF(!r.disableSymbolRenaming,
                             "Could not find remapped name for entry point.");
 
-            *remappedEntryPointName = request.entryPointName;
+            *remappedEntryPointName = r.entryPointName;
         }
     } else {
         return DAWN_FORMAT_VALIDATION_ERROR("Transform output missing renamer data.");
     }
 
+    if (r.stage == SingleShaderStage::Vertex) {
+        if (auto* data = transformOutputs.Get<tint::transform::FirstIndexOffset::Data>()) {
+            *usesVertexOrInstanceIndex = data->has_vertex_or_instance_index;
+        } else {
+            return DAWN_FORMAT_VALIDATION_ERROR(
+                "Transform output missing first index offset data.");
+        }
+    }
+
     tint::writer::hlsl::Options options;
-    options.disable_workgroup_init = request.disableWorkgroupInit;
-    if (request.usesNumWorkgroups) {
-        options.root_constant_binding_point = tint::sem::BindingPoint{
-            request.numWorkgroupsRegisterSpace, request.numWorkgroupsShaderRegister};
+    options.disable_workgroup_init = r.disableWorkgroupInit;
+    if (r.usesNumWorkgroups) {
+        options.root_constant_binding_point =
+            tint::sem::BindingPoint{r.numWorkgroupsRegisterSpace, r.numWorkgroupsShaderRegister};
     }
     // TODO(dawn:549): HLSL generation outputs the indices into the
     // array_length_from_uniform buffer that were actually used. When the blob cache can
     // store more than compiled shaders, we should reflect these used indices and store
     // them as well. This would allow us to only upload root constants that are actually
     // read by the shader.
-    options.array_length_from_uniform = request.arrayLengthFromUniform;
-    TRACE_EVENT0(platform, General, "tint::writer::hlsl::Generate");
+    options.array_length_from_uniform = r.arrayLengthFromUniform;
+    TRACE_EVENT0(tracePlatform.UnsafeGetValue(), General, "tint::writer::hlsl::Generate");
     auto result = tint::writer::hlsl::Generate(&transformedProgram, options);
     DAWN_INVALID_IF(!result.success, "An error occured while generating HLSL: %s", result.error);
 
     return std::move(result.hlsl);
 }
 
-template <typename F>
-MaybeError CompileShader(dawn::platform::Platform* platform,
-                         const PlatformFunctions* functions,
-                         IDxcLibrary* dxcLibrary,
-                         IDxcCompiler* dxcCompiler,
-                         ShaderCompilationRequest&& request,
-                         bool dumpShaders,
-                         F&& DumpShadersEmitLog,
-                         CompiledShader* compiledShader) {
+ResultOrError<CompiledShader> CompileShader(D3DCompilationRequest r) {
+    CompiledShader compiledShader;
     // Compile the source shader to HLSL.
-    std::string hlslSource;
     std::string remappedEntryPoint;
-    DAWN_TRY_ASSIGN(hlslSource, TranslateToHLSL(platform, request, &remappedEntryPoint));
-    if (dumpShaders) {
-        std::ostringstream dumpedMsg;
-        dumpedMsg << "/* Dumped generated HLSL */" << std::endl << hlslSource;
-        DumpShadersEmitLog(WGPULoggingType_Info, dumpedMsg.str().c_str());
-    }
-    request.entryPointName = remappedEntryPoint.c_str();
-    switch (request.compiler) {
-        case ShaderCompilationRequest::Compiler::DXC: {
-            TRACE_EVENT0(platform, General, "CompileShaderDXC");
-            DAWN_TRY_ASSIGN(compiledShader->compiledDXCShader,
-                            CompileShaderDXC(dxcLibrary, dxcCompiler, request, hlslSource));
+    DAWN_TRY_ASSIGN(compiledShader.hlslSource,
+                    TranslateToHLSL(std::move(r.hlsl), r.tracePlatform, &remappedEntryPoint,
+                                    &compiledShader.usesVertexOrInstanceIndex));
+
+    switch (r.bytecode.compiler) {
+        case Compiler::DXC: {
+            TRACE_EVENT0(r.tracePlatform.UnsafeGetValue(), General, "CompileShaderDXC");
+            ComPtr<IDxcBlob> compiledDXCShader;
+            DAWN_TRY_ASSIGN(compiledDXCShader, CompileShaderDXC(r.bytecode, remappedEntryPoint,
+                                                                compiledShader.hlslSource));
+            compiledShader.shaderBlob = CreateBlob(std::move(compiledDXCShader));
             break;
         }
-        case ShaderCompilationRequest::Compiler::FXC: {
-            TRACE_EVENT0(platform, General, "CompileShaderFXC");
-            DAWN_TRY_ASSIGN(compiledShader->compiledFXCShader,
-                            CompileShaderFXC(functions, request, hlslSource));
+        case Compiler::FXC: {
+            TRACE_EVENT0(r.tracePlatform.UnsafeGetValue(), General, "CompileShaderFXC");
+            ComPtr<ID3DBlob> compiledFXCShader;
+            DAWN_TRY_ASSIGN(compiledFXCShader, CompileShaderFXC(r.bytecode, remappedEntryPoint,
+                                                                compiledShader.hlslSource));
+            compiledShader.shaderBlob = CreateBlob(std::move(compiledFXCShader));
             break;
         }
     }
 
-    if (dumpShaders && request.compiler == ShaderCompilationRequest::Compiler::FXC) {
-        std::ostringstream dumpedMsg;
-        dumpedMsg << "/* FXC compile flags */ " << std::endl
-                  << CompileFlagsToStringFXC(request.compileFlags) << std::endl;
-
-        dumpedMsg << "/* Dumped disassembled DXBC */" << std::endl;
-
-        ComPtr<ID3DBlob> disassembly;
-        if (FAILED(functions->d3dDisassemble(compiledShader->compiledFXCShader->GetBufferPointer(),
-                                             compiledShader->compiledFXCShader->GetBufferSize(), 0,
-                                             nullptr, &disassembly))) {
-            dumpedMsg << "D3D disassemble failed" << std::endl;
-        } else {
-            dumpedMsg << reinterpret_cast<const char*>(disassembly->GetBufferPointer());
-        }
-        DumpShadersEmitLog(WGPULoggingType_Info, dumpedMsg.str().c_str());
+    // If dumpShaders is false, we don't need the HLSL for logging. Clear the contents so it
+    // isn't stored into the cache.
+    if (!r.hlsl.dumpShaders) {
+        compiledShader.hlslSource = "";
     }
-
-    return {};
+    return compiledShader;
 }
 
 }  // anonymous namespace
@@ -741,74 +549,202 @@
                                                     SingleShaderStage stage,
                                                     const PipelineLayout* layout,
                                                     uint32_t compileFlags) {
-    TRACE_EVENT0(GetDevice()->GetPlatform(), General, "ShaderModuleD3D12::Compile");
+    Device* device = ToBackend(GetDevice());
+    TRACE_EVENT0(device->GetPlatform(), General, "ShaderModuleD3D12::Compile");
     ASSERT(!IsError());
 
-    ScopedTintICEHandler scopedICEHandler(GetDevice());
+    ScopedTintICEHandler scopedICEHandler(device);
+    const EntryPointMetadata& entryPoint = GetEntryPoint(programmableStage.entryPoint);
 
-    Device* device = ToBackend(GetDevice());
+    D3DCompilationRequest req = {};
+    req.tracePlatform = UnsafeUnkeyedValue(device->GetPlatform());
+    req.hlsl.shaderModel = device->GetDeviceInfo().shaderModel;
+    req.hlsl.disableSymbolRenaming = device->IsToggleEnabled(Toggle::DisableSymbolRenaming);
+    req.hlsl.isRobustnessEnabled = device->IsRobustnessEnabled();
+    req.hlsl.disableWorkgroupInit = device->IsToggleEnabled(Toggle::DisableWorkgroupInit);
+    req.hlsl.dumpShaders = device->IsToggleEnabled(Toggle::DumpShaders);
 
-    CompiledShader compiledShader = {};
-
-    tint::transform::Manager transformManager;
-    tint::transform::DataMap transformInputs;
-
-    const tint::Program* program = GetTintProgram();
-    tint::Program programAsValue;
-
-    auto externalTextureBindings = BuildExternalTextureTransformBindings(layout);
-    if (!externalTextureBindings.empty()) {
-        transformManager.Add<tint::transform::MultiplanarExternalTexture>();
-        transformInputs.Add<tint::transform::MultiplanarExternalTexture::NewBindingPoints>(
-            std::move(externalTextureBindings));
-    }
-
-    if (stage == SingleShaderStage::Vertex) {
-        transformManager.Add<tint::transform::FirstIndexOffset>();
-        transformInputs.Add<tint::transform::FirstIndexOffset::BindingPoint>(
-            layout->GetFirstIndexOffsetShaderRegister(),
-            layout->GetFirstIndexOffsetRegisterSpace());
-    }
-
-    tint::transform::DataMap transformOutputs;
-    DAWN_TRY_ASSIGN(programAsValue, RunTransforms(&transformManager, program, transformInputs,
-                                                  &transformOutputs, nullptr));
-    program = &programAsValue;
-
-    if (stage == SingleShaderStage::Vertex) {
-        if (auto* data = transformOutputs.Get<tint::transform::FirstIndexOffset::Data>()) {
-            // TODO(dawn:549): Consider adding this information to the pipeline cache once we
-            // can store more than the shader blob in it.
-            compiledShader.usesVertexOrInstanceIndex = data->has_vertex_or_instance_index;
+    req.bytecode.hasShaderFloat16Feature = device->IsFeatureEnabled(Feature::ShaderFloat16);
+    req.bytecode.compileFlags = compileFlags;
+    req.bytecode.defineStrings =
+        GetOverridableConstantsDefines(programmableStage.constants, entryPoint.overrides);
+    if (device->IsToggleEnabled(Toggle::UseDXC)) {
+        req.bytecode.compiler = Compiler::DXC;
+        req.bytecode.dxcLibrary = device->GetDxcLibrary().Get();
+        req.bytecode.dxcCompiler = device->GetDxcCompiler().Get();
+        DAWN_TRY_ASSIGN(req.bytecode.compilerVersion,
+                        ToBackend(device->GetAdapter())->GetBackend()->GetDXCompilerVersion());
+        req.bytecode.dxcShaderProfile = device->GetDeviceInfo().shaderProfiles[stage];
+    } else {
+        req.bytecode.compiler = Compiler::FXC;
+        req.bytecode.d3dCompile = device->GetFunctions()->d3dCompile;
+        req.bytecode.compilerVersion = D3D_COMPILER_VERSION;
+        switch (stage) {
+            case SingleShaderStage::Vertex:
+                req.bytecode.fxcShaderProfile = "vs_5_1";
+                break;
+            case SingleShaderStage::Fragment:
+                req.bytecode.fxcShaderProfile = "ps_5_1";
+                break;
+            case SingleShaderStage::Compute:
+                req.bytecode.fxcShaderProfile = "cs_5_1";
+                break;
         }
     }
 
-    ShaderCompilationRequest request;
-    DAWN_TRY_ASSIGN(request,
-                    ShaderCompilationRequest::Create(
-                        programmableStage.entryPoint.c_str(), stage, layout, compileFlags, device,
-                        program, GetEntryPoint(programmableStage.entryPoint), programmableStage));
+    using tint::transform::BindingPoint;
+    using tint::transform::BindingRemapper;
 
-    // TODO(dawn:1341): Add shader cache key generation and caching for the compiled shader.
-    DAWN_TRY(CompileShader(
-        device->GetPlatform(), device->GetFunctions(),
-        device->IsToggleEnabled(Toggle::UseDXC) ? device->GetDxcLibrary().Get() : nullptr,
-        device->IsToggleEnabled(Toggle::UseDXC) ? device->GetDxcCompiler().Get() : nullptr,
-        std::move(request), device->IsToggleEnabled(Toggle::DumpShaders),
-        [&](WGPULoggingType loggingType, const char* message) {
-            GetDevice()->EmitLog(loggingType, message);
-        },
-        &compiledShader));
-    return std::move(compiledShader);
+    BindingRemapper::BindingPoints remappedBindingPoints;
+    BindingRemapper::AccessControls remappedAccessControls;
+
+    tint::writer::ArrayLengthFromUniformOptions arrayLengthFromUniform;
+    arrayLengthFromUniform.ubo_binding = {layout->GetDynamicStorageBufferLengthsRegisterSpace(),
+                                          layout->GetDynamicStorageBufferLengthsShaderRegister()};
+
+    const BindingInfoArray& moduleBindingInfo = entryPoint.bindings;
+    for (BindGroupIndex group : IterateBitSet(layout->GetBindGroupLayoutsMask())) {
+        const BindGroupLayout* bgl = ToBackend(layout->GetBindGroupLayout(group));
+        const auto& groupBindingInfo = moduleBindingInfo[group];
+
+        // d3d12::BindGroupLayout packs the bindings per HLSL register-space. We modify
+        // the Tint AST to make the "bindings" decoration match the offset chosen by
+        // d3d12::BindGroupLayout so that Tint produces HLSL with the correct registers
+        // assigned to each interface variable.
+        for (const auto& [binding, bindingInfo] : groupBindingInfo) {
+            BindingIndex bindingIndex = bgl->GetBindingIndex(binding);
+            BindingPoint srcBindingPoint{static_cast<uint32_t>(group),
+                                         static_cast<uint32_t>(binding)};
+            BindingPoint dstBindingPoint{static_cast<uint32_t>(group),
+                                         bgl->GetShaderRegister(bindingIndex)};
+            if (srcBindingPoint != dstBindingPoint) {
+                remappedBindingPoints.emplace(srcBindingPoint, dstBindingPoint);
+            }
+
+            // Declaring a read-only storage buffer in HLSL but specifying a storage
+            // buffer in the BGL produces the wrong output. Force read-only storage
+            // buffer bindings to be treated as UAV instead of SRV. Internal storage
+            // buffer is a storage buffer used in the internal pipeline.
+            const bool forceStorageBufferAsUAV =
+                (bindingInfo.buffer.type == wgpu::BufferBindingType::ReadOnlyStorage &&
+                 (bgl->GetBindingInfo(bindingIndex).buffer.type ==
+                      wgpu::BufferBindingType::Storage ||
+                  bgl->GetBindingInfo(bindingIndex).buffer.type == kInternalStorageBufferBinding));
+            if (forceStorageBufferAsUAV) {
+                remappedAccessControls.emplace(srcBindingPoint, tint::ast::Access::kReadWrite);
+            }
+        }
+
+        // Add arrayLengthFromUniform options
+        {
+            for (const auto& bindingAndRegisterOffset :
+                 layout->GetDynamicStorageBufferLengthInfo()[group].bindingAndRegisterOffsets) {
+                BindingNumber binding = bindingAndRegisterOffset.binding;
+                uint32_t registerOffset = bindingAndRegisterOffset.registerOffset;
+
+                BindingPoint bindingPoint{static_cast<uint32_t>(group),
+                                          static_cast<uint32_t>(binding)};
+                // Get the renamed binding point if it was remapped.
+                auto it = remappedBindingPoints.find(bindingPoint);
+                if (it != remappedBindingPoints.end()) {
+                    bindingPoint = it->second;
+                }
+
+                arrayLengthFromUniform.bindpoint_to_size_index.emplace(bindingPoint,
+                                                                       registerOffset);
+            }
+        }
+    }
+
+    req.hlsl.inputProgram = GetTintProgram();
+    req.hlsl.entryPointName = programmableStage.entryPoint.c_str();
+    req.hlsl.stage = stage;
+    req.hlsl.firstIndexOffsetShaderRegister = layout->GetFirstIndexOffsetShaderRegister();
+    req.hlsl.firstIndexOffsetRegisterSpace = layout->GetFirstIndexOffsetRegisterSpace();
+    req.hlsl.usesNumWorkgroups = entryPoint.usesNumWorkgroups;
+    req.hlsl.numWorkgroupsShaderRegister = layout->GetNumWorkgroupsShaderRegister();
+    req.hlsl.numWorkgroupsRegisterSpace = layout->GetNumWorkgroupsRegisterSpace();
+    req.hlsl.remappedBindingPoints = std::move(remappedBindingPoints);
+    req.hlsl.remappedAccessControls = std::move(remappedAccessControls);
+    req.hlsl.newBindingsMap = BuildExternalTextureTransformBindings(layout);
+    req.hlsl.arrayLengthFromUniform = std::move(arrayLengthFromUniform);
+
+    CacheResult<CompiledShader> compiledShader;
+    DAWN_TRY_LOAD_OR_RUN(compiledShader, device, std::move(req), CompiledShader::FromBlob,
+                         CompileShader);
+
+    if (device->IsToggleEnabled(Toggle::DumpShaders)) {
+        std::ostringstream dumpedMsg;
+        dumpedMsg << "/* Dumped generated HLSL */" << std::endl
+                  << compiledShader->hlslSource << std::endl;
+        device->EmitLog(WGPULoggingType_Info, dumpedMsg.str().c_str());
+
+        if (device->IsToggleEnabled(Toggle::UseDXC)) {
+            dumpedMsg << "/* Dumped disassembled DXIL */" << std::endl;
+            D3D12_SHADER_BYTECODE code = compiledShader->GetD3D12ShaderBytecode();
+            ComPtr<IDxcBlobEncoding> dxcBlob;
+            ComPtr<IDxcBlobEncoding> disassembly;
+            if (FAILED(device->GetDxcLibrary()->CreateBlobWithEncodingFromPinned(
+                    code.pShaderBytecode, code.BytecodeLength, 0, &dxcBlob)) ||
+                FAILED(device->GetDxcCompiler()->Disassemble(dxcBlob.Get(), &disassembly))) {
+                dumpedMsg << "DXC disassemble failed" << std::endl;
+            } else {
+                dumpedMsg << std::string_view(
+                    static_cast<const char*>(disassembly->GetBufferPointer()),
+                    disassembly->GetBufferSize());
+            }
+        } else {
+            dumpedMsg << "/* FXC compile flags */ " << std::endl
+                      << CompileFlagsToStringFXC(compileFlags) << std::endl;
+            dumpedMsg << "/* Dumped disassembled DXBC */" << std::endl;
+            ComPtr<ID3DBlob> disassembly;
+            D3D12_SHADER_BYTECODE code = compiledShader->GetD3D12ShaderBytecode();
+            if (FAILED(device->GetFunctions()->d3dDisassemble(
+                    code.pShaderBytecode, code.BytecodeLength, 0, nullptr, &disassembly))) {
+                dumpedMsg << "D3D disassemble failed" << std::endl;
+            } else {
+                dumpedMsg << std::string_view(
+                    static_cast<const char*>(disassembly->GetBufferPointer()),
+                    disassembly->GetBufferSize());
+            }
+        }
+        device->EmitLog(WGPULoggingType_Info, dumpedMsg.str().c_str());
+    }
+
+    if (BlobCache* cache = device->GetBlobCache()) {
+        cache->EnsureStored(compiledShader);
+    }
+
+    // Clear the hlslSource. It is only used for logging and should not be used
+    // outside of the compilation.
+    CompiledShader result = compiledShader.Acquire();
+    result.hlslSource = "";
+    return result;
 }
 
 D3D12_SHADER_BYTECODE CompiledShader::GetD3D12ShaderBytecode() const {
-    if (compiledFXCShader != nullptr) {
-        return {compiledFXCShader->GetBufferPointer(), compiledFXCShader->GetBufferSize()};
-    } else if (compiledDXCShader != nullptr) {
-        return {compiledDXCShader->GetBufferPointer(), compiledDXCShader->GetBufferSize()};
-    }
-    UNREACHABLE();
-    return {};
+    return {shaderBlob.Data(), shaderBlob.Size()};
 }
+
 }  // namespace dawn::native::d3d12
+
+namespace dawn::native {
+
+// Define the implementation to store d3d12::CompiledShader into the BlobCache.
+template <>
+void BlobCache::Store<d3d12::CompiledShader>(const CacheKey& key, const d3d12::CompiledShader& c) {
+    stream::ByteVectorSink sink;
+    c.VisitAll([&](const auto&... members) { StreamIn(&sink, members...); });
+    Store(key, CreateBlob(std::move(sink)));
+}
+
+// Define the implementation to load d3d12::CompiledShader from a Blob.
+// static
+ResultOrError<d3d12::CompiledShader> d3d12::CompiledShader::FromBlob(Blob blob) {
+    stream::BlobSource source(std::move(blob));
+    d3d12::CompiledShader c;
+    DAWN_TRY(c.VisitAll([&](auto&... members) { return StreamOut(&source, &members...); }));
+    return c;
+}
+
+}  // namespace dawn::native
diff --git a/src/dawn/native/d3d12/ShaderModuleD3D12.h b/src/dawn/native/d3d12/ShaderModuleD3D12.h
index 7f68b10..528e1e4 100644
--- a/src/dawn/native/d3d12/ShaderModuleD3D12.h
+++ b/src/dawn/native/d3d12/ShaderModuleD3D12.h
@@ -15,8 +15,11 @@
 #ifndef SRC_DAWN_NATIVE_D3D12_SHADERMODULED3D12_H_
 #define SRC_DAWN_NATIVE_D3D12_SHADERMODULED3D12_H_
 
-#include "dawn/native/ShaderModule.h"
+#include <string>
 
+#include "dawn/native/Blob.h"
+#include "dawn/native/ShaderModule.h"
+#include "dawn/native/VisitableMembers.h"
 #include "dawn/native/d3d12/d3d12_platform.h"
 
 namespace dawn::native {
@@ -28,14 +31,22 @@
 class Device;
 class PipelineLayout;
 
-// Manages a ref to one of the various representations of shader blobs and information used to
-// emulate vertex/instance index starts
+#define COMPILED_SHADER_MEMBERS(X) \
+    X(Blob, shaderBlob)            \
+    X(std::string, hlslSource)     \
+    X(bool, usesVertexOrInstanceIndex)
+
+// `CompiledShader` holds a ref to one of the various representations of shader blobs and
+// information used to emulate vertex/instance index starts. It also holds the `hlslSource` for the
+// shader compilation, which is only transiently available during Compile, and cleared before it
+// returns. It is not written to or loaded from the cache unless Toggle dump_shaders is true.
 struct CompiledShader {
-    ComPtr<ID3DBlob> compiledFXCShader;
-    ComPtr<IDxcBlob> compiledDXCShader;
+    static ResultOrError<CompiledShader> FromBlob(Blob blob);
+
     D3D12_SHADER_BYTECODE GetD3D12ShaderBytecode() const;
 
-    bool usesVertexOrInstanceIndex;
+    DAWN_VISITABLE_MEMBERS(COMPILED_SHADER_MEMBERS)
+#undef COMPILED_SHADER_MEMBERS
 };
 
 class ShaderModule final : public ShaderModuleBase {
diff --git a/src/dawn/native/d3d12/UtilsD3D12.cpp b/src/dawn/native/d3d12/UtilsD3D12.cpp
index 0e761f8..e706d8f 100644
--- a/src/dawn/native/d3d12/UtilsD3D12.cpp
+++ b/src/dawn/native/d3d12/UtilsD3D12.cpp
@@ -81,19 +81,19 @@
 
 }  // anonymous namespace
 
-ResultOrError<std::wstring> ConvertStringToWstring(const char* str) {
-    size_t len = strlen(str);
+ResultOrError<std::wstring> ConvertStringToWstring(std::string_view s) {
+    size_t len = s.length();
     if (len == 0) {
         return std::wstring();
     }
-    int numChars = MultiByteToWideChar(CP_UTF8, MB_ERR_INVALID_CHARS, str, len, nullptr, 0);
+    int numChars = MultiByteToWideChar(CP_UTF8, MB_ERR_INVALID_CHARS, s.data(), len, nullptr, 0);
     if (numChars == 0) {
         return DAWN_INTERNAL_ERROR("Failed to convert string to wide string");
     }
     std::wstring result;
     result.resize(numChars);
     int numConvertedChars =
-        MultiByteToWideChar(CP_UTF8, MB_ERR_INVALID_CHARS, str, len, &result[0], numChars);
+        MultiByteToWideChar(CP_UTF8, MB_ERR_INVALID_CHARS, s.data(), len, &result[0], numChars);
     if (numConvertedChars != numChars) {
         return DAWN_INTERNAL_ERROR("Failed to convert string to wide string");
     }
diff --git a/src/dawn/native/d3d12/UtilsD3D12.h b/src/dawn/native/d3d12/UtilsD3D12.h
index 1418f54..dcbe782 100644
--- a/src/dawn/native/d3d12/UtilsD3D12.h
+++ b/src/dawn/native/d3d12/UtilsD3D12.h
@@ -26,7 +26,7 @@
 
 namespace dawn::native::d3d12 {
 
-ResultOrError<std::wstring> ConvertStringToWstring(const char* str);
+ResultOrError<std::wstring> ConvertStringToWstring(std::string_view s);
 
 D3D12_COMPARISON_FUNC ToD3D12ComparisonFunc(wgpu::CompareFunction func);
 
diff --git a/src/dawn/native/stream/Stream.cpp b/src/dawn/native/stream/Stream.cpp
index 1ca241c..beb3823 100644
--- a/src/dawn/native/stream/Stream.cpp
+++ b/src/dawn/native/stream/Stream.cpp
@@ -48,4 +48,14 @@
     }
 }
 
+template <>
+void Stream<std::wstring_view>::Write(Sink* s, const std::wstring_view& t) {
+    StreamIn(s, t.length());
+    size_t size = t.length() * sizeof(wchar_t);
+    if (size > 0) {
+        void* ptr = s->GetSpace(size);
+        memcpy(ptr, t.data(), size);
+    }
+}
+
 }  // namespace dawn::native::stream
diff --git a/src/dawn/native/stream/Stream.h b/src/dawn/native/stream/Stream.h
index 3433317..d077cccc 100644
--- a/src/dawn/native/stream/Stream.h
+++ b/src/dawn/native/stream/Stream.h
@@ -297,10 +297,9 @@
   public:
     static void Write(stream::Sink* sink, const std::unordered_map<K, V>& m) {
         std::vector<std::pair<K, V>> ordered(m.begin(), m.end());
-        std::sort(ordered.begin(), ordered.end(),
-                  [](const std::pair<K, V>& a, const std::pair<K, V>& b) {
-                      return std::less<K>{}(a.first, b.first);
-                  });
+        std::sort(
+            ordered.begin(), ordered.end(),
+            [](const std::pair<K, V>& a, const std::pair<K, V>& b) { return a.first < b.first; });
         StreamIn(sink, ordered);
     }
 };
diff --git a/src/dawn/tests/end2end/PipelineCachingTests.cpp b/src/dawn/tests/end2end/PipelineCachingTests.cpp
index 5dcf918..cbf5a92 100644
--- a/src/dawn/tests/end2end/PipelineCachingTests.cpp
+++ b/src/dawn/tests/end2end/PipelineCachingTests.cpp
@@ -108,8 +108,8 @@
     const EntryCounts counts = {
         // pipeline caching is only implemented on D3D12/Vulkan
         IsD3D12() || IsVulkan() ? 1u : 0u,
-        // shader module caching is only implemented on Vulkan/Metal
-        IsVulkan() || IsMetal() ? 1u : 0u,
+        // shader module caching is only implemented on Vulkan/D3D12/Metal
+        IsVulkan() || IsMetal() || IsD3D12() ? 1u : 0u,
     };
     NiceMock<CachingInterfaceMock> mMockCache;
 };
@@ -646,6 +646,7 @@
 
 DAWN_INSTANTIATE_TEST(SinglePipelineCachingTests,
                       D3D12Backend({"enable_blob_cache"}),
+                      D3D12Backend({"enable_blob_cache", "use_dxc"}),
                       MetalBackend({"enable_blob_cache"}),
                       OpenGLBackend({"enable_blob_cache"}),
                       OpenGLESBackend({"enable_blob_cache"}),
diff --git a/src/dawn/tests/unittests/native/StreamTests.cpp b/src/dawn/tests/unittests/native/StreamTests.cpp
index 6f25700..a1196f3 100644
--- a/src/dawn/tests/unittests/native/StreamTests.cpp
+++ b/src/dawn/tests/unittests/native/StreamTests.cpp
@@ -174,6 +174,30 @@
     EXPECT_CACHE_KEY_EQ(str, expected);
 }
 
+// Test that ByteVectorSink serializes std::wstring_views as expected.
+TEST(SerializeTests, StdWStringViews) {
+    static constexpr std::wstring_view str(L"Hello world!");
+
+    ByteVectorSink expected;
+    StreamIn(&expected, size_t(str.length()));
+    size_t bytes = str.length() * sizeof(wchar_t);
+    memcpy(expected.GetSpace(bytes), str.data(), bytes);
+
+    EXPECT_CACHE_KEY_EQ(str, expected);
+}
+
+// Test that ByteVectorSink serializes Blobs as expected.
+TEST(SerializeTests, Blob) {
+    uint8_t data[] = "dawn native Blob";
+    Blob blob = Blob::UnsafeCreateWithDeleter(data, sizeof(data), []() {});
+
+    ByteVectorSink expected;
+    StreamIn(&expected, sizeof(data));
+    expected.insert(expected.end(), data, data + sizeof(data));
+
+    EXPECT_CACHE_KEY_EQ(blob, expected);
+}
+
 // Test that ByteVectorSink serializes other ByteVectorSinks as expected.
 TEST(SerializeTests, ByteVectorSinks) {
     ByteVectorSink data = {'d', 'a', 't', 'a'};
@@ -309,6 +333,41 @@
     }
 }
 
+// Test that serializing then deserializing a Blob yields the same data.
+// Tested here instead of in the type-parameterized tests since Blobs are not copyable.
+TEST(StreamTests, SerializeDeserializeBlobs) {
+    // Test an empty blob
+    {
+        Blob blob;
+        EXPECT_EQ(blob.Size(), 0u);
+
+        ByteVectorSink sink;
+        StreamIn(&sink, blob);
+
+        BlobSource src(CreateBlob(sink));
+        Blob out;
+        auto err = StreamOut(&src, &out);
+        EXPECT_FALSE(err.IsError());
+        EXPECT_EQ(blob.Size(), out.Size());
+        EXPECT_EQ(memcmp(blob.Data(), out.Data(), blob.Size()), 0);
+    }
+
+    // Test a blob with some data
+    {
+        Blob blob = CreateBlob(std::vector<double>{6.24, 3.12222});
+
+        ByteVectorSink sink;
+        StreamIn(&sink, blob);
+
+        BlobSource src(CreateBlob(sink));
+        Blob out;
+        auto err = StreamOut(&src, &out);
+        EXPECT_FALSE(err.IsError());
+        EXPECT_EQ(blob.Size(), out.Size());
+        EXPECT_EQ(memcmp(blob.Data(), out.Data(), blob.Size()), 0);
+    }
+}
+
 template <size_t N>
 std::bitset<N - 1> BitsetFromBitString(const char (&str)[N]) {
     // N - 1 because the last character is the null terminator.