diff --git a/BUILD.gn b/BUILD.gn
index 6c7a192..d50d3cb 100644
--- a/BUILD.gn
+++ b/BUILD.gn
@@ -250,6 +250,8 @@
     "src/ast/import.h",
     "src/ast/int_literal.cc",
     "src/ast/int_literal.h",
+    "src/ast/intrinsic.cc",
+    "src/ast/intrinsic.h",
     "src/ast/kill_statement.cc",
     "src/ast/kill_statement.h",
     "src/ast/literal.cc",
@@ -686,6 +688,7 @@
     "src/writer/spirv/builder_global_variable_test.cc",
     "src/writer/spirv/builder_ident_expression_test.cc",
     "src/writer/spirv/builder_if_test.cc",
+    "src/writer/spirv/builder_intrinsic_test.cc",
     "src/writer/spirv/builder_kill_test.cc",
     "src/writer/spirv/builder_literal_test.cc",
     "src/writer/spirv/builder_loop_test.cc",
diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
index b18b1d4..4292b9a 100644
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -87,6 +87,8 @@
   ast/import.h
   ast/int_literal.cc
   ast/int_literal.h
+  ast/intrinsic.cc
+  ast/intrinsic.h
   ast/kill_statement.cc
   ast/kill_statement.h
   ast/literal.h
@@ -422,6 +424,7 @@
     writer/spirv/builder_global_variable_test.cc
     writer/spirv/builder_ident_expression_test.cc
     writer/spirv/builder_if_test.cc
+    writer/spirv/builder_intrinsic_test.cc
     writer/spirv/builder_kill_test.cc
     writer/spirv/builder_literal_test.cc
     writer/spirv/builder_loop_test.cc
diff --git a/src/ast/intrinsic.cc b/src/ast/intrinsic.cc
new file mode 100644
index 0000000..30311f5
--- /dev/null
+++ b/src/ast/intrinsic.cc
@@ -0,0 +1,40 @@
+// Copyright 2020 The Tint Authors.
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+#include "src/ast/intrinsic.h"
+
+namespace tint {
+namespace ast {
+namespace intrinsic {
+
+bool IsDerivative(const std::string& name) {
+  return name == "dpdx" || name == "dpdx_fine" || name == "dpdx_coarse" ||
+         name == "dpdy" || name == "dpdy_fine" || name == "dpdy_coarse" ||
+         name == "fwidth" || name == "fwidth_fine" || name == "fwidth_coarse";
+}
+
+bool IsFloatClassificationIntrinsic(const std::string& name) {
+  return name == "is_finite" || name == "is_inf" || name == "is_nan" ||
+         name == "is_normal";
+}
+
+bool IsIntrinsic(const std::string& name) {
+  return IsDerivative(name) || name == "all" || name == "any" ||
+         IsFloatClassificationIntrinsic(name) || name == "dot" ||
+         name == "outer_product";
+}
+
+}  // namespace intrinsic
+}  // namespace ast
+}  // namespace tint
diff --git a/src/ast/intrinsic.h b/src/ast/intrinsic.h
new file mode 100644
index 0000000..f827b29
--- /dev/null
+++ b/src/ast/intrinsic.h
@@ -0,0 +1,43 @@
+// Copyright 2020 The Tint Authors.
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+#ifndef SRC_AST_INTRINSIC_H_
+#define SRC_AST_INTRINSIC_H_
+
+#include <string>
+
+namespace tint {
+namespace ast {
+namespace intrinsic {
+
+/// Determine if the given |name | is a derivative intrinsic
+/// @param name the name to check
+/// @returns true if the given |name| is a derivative intrinsic
+bool IsDerivative(const std::string& name);
+
+/// Determines if the given |name| is a float classification intrinsic
+/// @param name the name to check
+/// @returns true if the given |name| is a float intrinsic
+bool IsFloatClassificationIntrinsic(const std::string& name);
+
+/// Determines if the given |name| is an intrinsic
+/// @param name the name to check
+/// @returns true if the given |name| is an intrinsic
+bool IsIntrinsic(const std::string& name);
+
+}  // namespace intrinsic
+}  // namespace ast
+}  // namespace tint
+
+#endif  // SRC_AST_INTRINSIC_H_
diff --git a/src/type_determiner.cc b/src/type_determiner.cc
index 4a562df..8d455bd 100644
--- a/src/type_determiner.cc
+++ b/src/type_determiner.cc
@@ -29,6 +29,7 @@
 #include "src/ast/else_statement.h"
 #include "src/ast/identifier_expression.h"
 #include "src/ast/if_statement.h"
+#include "src/ast/intrinsic.h"
 #include "src/ast/loop_statement.h"
 #include "src/ast/member_accessor_expression.h"
 #include "src/ast/return_statement.h"
@@ -46,25 +47,6 @@
 #include "src/ast/variable_decl_statement.h"
 
 namespace tint {
-namespace {
-
-bool IsDerivative(const std::string& name) {
-  return name == "dpdx" || name == "dpdx_fine" || name == "dpdx_coarse" ||
-         name == "dpdy" || name == "dpdy_fine" || name == "dpdy_coarse" ||
-         name == "fwidth" || name == "fwidth_fine" || name == "fwidth_coarse";
-}
-
-bool IsFloatIntrinsic(const std::string& name) {
-  return name == "is_finite" || name == "is_inf" || name == "is_nan" ||
-         name == "is_normal";
-}
-
-bool IsIntrinsic(const std::string& name) {
-  return IsDerivative(name) || name == "all" || name == "any" ||
-         IsFloatIntrinsic(name) || name == "dot" || name == "outer_product";
-}
-
-}  // namespace
 
 TypeDeterminer::TypeDeterminer(Context* ctx, ast::Module* mod)
     : ctx_(*ctx), mod_(mod) {}
@@ -321,7 +303,7 @@
   if (expr->func()->IsIdentifier()) {
     auto* ident = expr->func()->AsIdentifier();
 
-    if (IsIntrinsic(ident->name())) {
+    if (ast::intrinsic::IsIntrinsic(ident->name())) {
       if (!DetermineIntrinsic(ident->name(), expr))
         return false;
 
@@ -364,7 +346,7 @@
 
 bool TypeDeterminer::DetermineIntrinsic(const std::string& name,
                                         ast::CallExpression* expr) {
-  if (IsDerivative(name)) {
+  if (ast::intrinsic::IsDerivative(name)) {
     if (expr->params().size() != 1) {
       set_error(expr->source(), "incorrect number of parameters for " + name);
       return false;
@@ -383,7 +365,7 @@
         ctx_.type_mgr().Get(std::make_unique<ast::type::BoolType>()));
     return true;
   }
-  if (IsFloatIntrinsic(name)) {
+  if (ast::intrinsic::IsFloatClassificationIntrinsic(name)) {
     if (expr->params().size() != 1) {
       set_error(expr->source(), "incorrect number of parameters for " + name);
       return false;
diff --git a/src/writer/spirv/builder.cc b/src/writer/spirv/builder.cc
index 7feaab3..7d34b2f 100644
--- a/src/writer/spirv/builder.cc
+++ b/src/writer/spirv/builder.cc
@@ -33,6 +33,7 @@
 #include "src/ast/float_literal.h"
 #include "src/ast/identifier_expression.h"
 #include "src/ast/if_statement.h"
+#include "src/ast/intrinsic.h"
 #include "src/ast/location_decoration.h"
 #include "src/ast/loop_statement.h"
 #include "src/ast/member_accessor_expression.h"
@@ -1163,15 +1164,23 @@
 }
 
 uint32_t Builder::GenerateCallExpression(ast::CallExpression* expr) {
-  // TODO(dsinclair): Support regular function calls
-  if (!expr->func()->IsIdentifier() ||
-      !expr->func()->AsIdentifier()->has_path()) {
-    error_ = "function calls not supported yet.";
+  if (!expr->func()->IsIdentifier()) {
+    error_ = "invalid function name";
     return 0;
   }
 
   auto* ident = expr->func()->AsIdentifier();
 
+  if (!ident->has_path() && ast::intrinsic::IsIntrinsic(ident->name())) {
+    return GenerateIntrinsic(ident->name(), expr);
+  }
+
+  // TODO(dsinclair): Support regular function calls
+  if (!ident->has_path()) {
+    error_ = "function calls not supported yet.";
+    return 0;
+  }
+
   auto type_id = GenerateTypeIfNeeded(expr->func()->result_type());
   if (type_id == 0) {
     return 0;
@@ -1215,6 +1224,40 @@
   return result_id;
 }
 
+uint32_t Builder::GenerateIntrinsic(const std::string& name,
+                                    ast::CallExpression* call) {
+  auto result = result_op();
+  auto result_id = result.to_i();
+
+  auto result_type_id = GenerateTypeIfNeeded(call->result_type());
+  if (result_type_id == 0) {
+    return 0;
+  }
+
+  std::vector<Operand> params = {Operand::Int(result_type_id), result};
+  for (const auto& p : call->params()) {
+    auto val_id = GenerateExpression(p.get());
+    if (val_id == 0) {
+      return 0;
+    }
+    val_id = GenerateLoadIfNeeded(p->result_type(), val_id);
+
+    params.push_back(Operand::Int(val_id));
+  }
+
+  spv::Op op = spv::Op::OpNop;
+  if (name == "any") {
+    op = spv::Op::OpAny;
+  }
+  if (op == spv::Op::OpNop) {
+    error_ = "unable to determine operator for: " + name;
+    return 0;
+  }
+  push_function_inst(op, params);
+
+  return result_id;
+}
+
 uint32_t Builder::GenerateCastExpression(ast::CastExpression* cast) {
   auto result = result_op();
   auto result_id = result.to_i();
diff --git a/src/writer/spirv/builder.h b/src/writer/spirv/builder.h
index 2a6fd65..5a43021 100644
--- a/src/writer/spirv/builder.h
+++ b/src/writer/spirv/builder.h
@@ -286,6 +286,12 @@
   /// @param expr the expression to generate
   /// @returns the expression ID on success or 0 otherwise
   uint32_t GenerateCallExpression(ast::CallExpression* expr);
+  /// Generates an intrinsic call
+  /// @param name the intrinsic name
+  /// @param call the call expression
+  /// @returns the expression ID on success or 0 otherwise
+  uint32_t GenerateIntrinsic(const std::string& name,
+                             ast::CallExpression* call);
   /// Generates a cast expression
   /// @param expr the expression to generate
   /// @returns the expression ID on success or 0 otherwise
diff --git a/src/writer/spirv/builder_intrinsic_test.cc b/src/writer/spirv/builder_intrinsic_test.cc
new file mode 100644
index 0000000..054f9f4
--- /dev/null
+++ b/src/writer/spirv/builder_intrinsic_test.cc
@@ -0,0 +1,74 @@
+// Copyright 2020 The Tint Authors.
+//
+// Licensed under the Apache License, Version 2.0 (the "License");
+// you may not use this file except in compliance with the License.
+// You may obtain a copy of the License at
+//
+//     http://www.apache.org/licenses/LICENSE-2.0
+//
+// Unless required by applicable law or agreed to in writing, software
+// distributed under the License is distributed on an "AS IS" BASIS,
+// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+// See the License for the specific language governing permissions and
+// limitations under the License.
+
+#include <memory>
+
+#include "gtest/gtest.h"
+#include "src/ast/call_expression.h"
+#include "src/ast/identifier_expression.h"
+#include "src/ast/type/bool_type.h"
+#include "src/ast/type/vector_type.h"
+#include "src/ast/variable.h"
+#include "src/context.h"
+#include "src/type_determiner.h"
+#include "src/writer/spirv/builder.h"
+#include "src/writer/spirv/spv_dump.h"
+
+namespace tint {
+namespace writer {
+namespace spirv {
+namespace {
+
+using BuilderTest = testing::Test;
+
+TEST_F(BuilderTest, Call_Any) {
+  ast::type::BoolType bool_type;
+  ast::type::VectorType vec3(&bool_type, 3);
+
+  auto var =
+      std::make_unique<ast::Variable>("v", ast::StorageClass::kPrivate, &vec3);
+
+  ast::ExpressionList params;
+  params.push_back(std::make_unique<ast::IdentifierExpression>("v"));
+  ast::CallExpression expr(std::make_unique<ast::IdentifierExpression>("any"),
+                           std::move(params));
+
+  Context ctx;
+  ast::Module mod;
+  TypeDeterminer td(&ctx, &mod);
+  td.RegisterVariableForTesting(var.get());
+
+  ASSERT_TRUE(td.DetermineResultType(&expr)) << td.error();
+
+  Builder b(&mod);
+  b.push_function(Function{});
+  ASSERT_TRUE(b.GenerateGlobalVariable(var.get())) << b.error();
+
+  EXPECT_EQ(b.GenerateCallExpression(&expr), 6u) << b.error();
+  EXPECT_EQ(DumpInstructions(b.types()), R"(%4 = OpTypeBool
+%3 = OpTypeVector %4 3
+%2 = OpTypePointer Private %3
+%5 = OpConstantNull %3
+%1 = OpVariable %2 Private %5
+)");
+  EXPECT_EQ(DumpInstructions(b.functions()[0].instructions()),
+            R"(%7 = OpLoad %3 %1
+%6 = OpAny %4 %7
+)");
+}
+
+}  // namespace
+}  // namespace spirv
+}  // namespace writer
+}  // namespace tint